The 6th Computational Structural Bioinformatics Workshop

6th Workshop on Computational Models of Narrative

Since narrative is a foundational framework for the on-going co-evolution of human cognition and culture, the advent of computation as a new medium for representing narratives offers the promise of ratcheting up human understanding and expressive power, just as previous media of representation like language and writing have done. But digital representation often produces artifacts that are stor...

Computational Structural Bioinformatics II: Molecular Models

6th Workshop on Ontologies and Lexical Resources

This document describes an open text-mining system that was developed for the Asian-European project KYOTO. The KYOTO system uses an open text representation format and a central ontology to enable extraction of knowledge and facts from large volumes of text in many different languages. We implemented a semantic tagging approach that performs off-line reasoning. Mining of facts and knowledge is...

Structural bioinformatics Computational identification of MoRFs in protein sequences

Motivation: Intrinsically disordered regions of proteins play an essential role in the regulation of various biological processes. Key to their regulatory function is the binding of molecular recognition features (MoRFs) to globular protein domains in a process known as a disorder-to-order transition. Predicting the location of MoRFs in protein sequences with high accuracy remains an important ...

Achievements and challenges in structural bioinformatics and computational biophysics

MOTIVATION The field of structural bioinformatics and computational biophysics has undergone a revolution in the last 10 years. Developments that are captured annually through the 3DSIG meeting, upon which this article reflects. RESULTS An increase in the accessible data, computational resources and methodology has resulted in an increase in the size and resolution of studied systems and the ...